Treating Centralized Corneal Neuropathic Pain (CCP)

Centralized pain is a recognized neuropathic disease in the pain world, but is foreign to ophthalmologists. Corneal centralized pain (CCP) is generated in the CNS pain circuitry and becomes entrenched by alterations in the functional, biochemical and anatomic features of the nociceptive pathways and the somatosensory cortex, consequences of maladaptive neuroplasticity. The features associated with […]

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Agonizing Pain Caused by Diseases of the Corneal Nerve System Can Be Invisible

Diseased corneal nerves and their connections in the brain can cause intense eye pain. This includes pain similar to dry eye, non-dry eye pain, and disabling photosensitivity – which can not be detected through the appearance of the eye The terminals of the abundant nerves located just below the corneal surface are specialized to function […]

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When “Dry Eye” Isn’t Dry: Tears Are Not Always the Explanation

Dry Eye Disease is the diagnosis given to eyes that feel unusually dry, whether or not they are dry. Dry eye symptoms are a unique type of pain that originates in the nerves of the highly sensitive cornea, the dome-shaped, transparent front surface of our eyes behind which our colored iris and black pupil are […]

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